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The study aims to evaluate bone tumor characteristics and the agreement between radiological and histopathological diagnoses.

June 7, 2026CureusOpen Access

Radiological and Histopathological Correlative Analysis of Bone Tumors and Tumor-Like Lesions at a Tertiary Care Center

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The study aims to evaluate bone tumor characteristics and the agreement between radiological and histopathological diagnoses.
Conducted at a tertiary care hospital over 18 months with 125 patients with suspected bone lesions.
Biopsy or surgical intervention was performed for histopathological examination.
Concordance was assessed using Cohen’s kappa statistic with a significance threshold of p<0.05.
Radiological findings categorized 52 lesions as malignant, while histopathology confirmed malignancy in 47 cases.
Moderate agreement was found between the two diagnostic modalities with 106 cases showing concordance (85%), kappa value 0.636.
Osteosarcoma was the most common malignant tumor identified.

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Prospective observational study evaluates bone tumor diagnostics, highlighting concordance between imaging and pathology.

Kumari et al. (2026) studied this question.

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