Why the study?
Diabetes mellitus and hematological disorders pose substantial, intersecting health challenges in the US, but long-term national mortality trends were uncharacterized.
Population
217,168 deaths attributed to hematological disorders and diabetes mellitus in the US
Comparison
Demographic and geographic subgroups
Design
Retrospective epidemiological study using CDC WONDER data and Joinpoint regression
Key result
Between 1999 and 2020, US mortality rates for diabetes and hematological disorders increased significantly, with the sharpest rise occurring from 2018 to 2020 (APC 18.20).
Authors
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Comorbid diabetes and hematological disorders warrant clinical vigilance; this observational study leaves open modifiable risk factors and intervention targets.
Observational (n=217,168)
Yes
Mortality attributed to diabetes and hematological disorders in the US increased significantly from 1999 to 2020, with a sharp rise between 2018 and 2020 and notable geographic and demographic disparities.
Saeed et al. (2026) conducted an observational in Diabetes mellitus and hematological disorders (n=217,168). Time period (1999-2020) and demographic/geographic factors was evaluated on Age-adjusted mortality rates (AAMR) per 100,000 for DM and HD as contributing causes of death. Between 1999 and 2020, US mortality rates for diabetes and hematological disorders increased significantly, with the sharpest rise occurring from 2018 to 2020 (APC 18.20).