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January 1, 2026Organic & Biomolecular ChemistryOpen Access

Cu-catalyzed oxidative coupling of alkylarenes with tertiary C(sp ³ )–H bonds via C–H activation

Gang Hong Pradip D. Nahide Wahiduddin G. Patel Marisa C. Kozlowski

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Key Points

This research aims to explore the efficiency of Cu-catalyzed oxidative coupling involving alkylarenes and tertiary C(sp3)–H bonds.
Utilized Cu-catalyzed cross-dehydrogenative coupling (CDC).
Focused on the activation of tertiary C(sp3)–H bonds.
Analyzed reaction efficiency and product formation.
Demonstrated efficient coupling with a high yield of desired products.
Showed favorable conditions for activating tertiary C(sp3)–H bonds.

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Implication

Demonstrates efficient C–H activation in alkylarenes, suggesting a novel catalytic approach.

Abstract

Efficient Cu-catalyzed CDC of alkylarenes with tertiary C(sp 3 )–H Bonds via C–H activation.

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Cite This Study

Hong et al. (2026) studied this question.

synapsesocial.com/papers/6a250cd27def13d035e1d042 https://doi.org/10.1039/d6ob00723f

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3Cross-dehydrogenative coupling via C(sp2025 · 6 citations
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