Why the study?
Aerobic exercise training is a cornerstone treatment for obesity and type 2 diabetes, but cardiometabolic adaptations vary widely among individuals.
Does 15-week supervised aerobic exercise training alter cardiometabolic measures differently based on cardiorespiratory fitness response in adults with obesity with and without T2D?
Population
36 adults with obesity, 39% with T2D
Comparison
AET responders (peak VO2 change > 0) vs non-responders (peak VO2 change <= 0)
Follow-up
15 weeks
Key result
A 15-week aerobic exercise training program in adults with obesity elicited heterogeneous adaptations, with responders showing significant differences in max workload (P<0.001) and ejection fraction (P=0.013).
Authors
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May inform tailored exercise programs for adults with obesity; leaves open determinants of heterogeneous adaptations in prospective trials.
Cohort (n=36)
Does 15-week supervised aerobic exercise training alter cardiometabolic measures differently based on cardiorespiratory fitness response in adults with obesity with and without T2D?
Effect estimate: η² 0.31
p-value: p=<0.001
A 15-week supervised aerobic exercise training program elicits heterogeneous physiological adaptations in adults with obesity, with significant differences in max workload and ejection fraction between peak VO2 responders and non-responders.
Park et al. (2026) conducted a cohort in Obesity with and without Type 2 Diabetes (n=36). Aerobic exercise training (AET) vs. Non-responders (change in peak VO2 ≤ 0) was evaluated on Max workload and ejection fraction (η² 0.31, p=<0.001). A 15-week aerobic exercise training program in adults with obesity elicited heterogeneous adaptations, with responders showing significant differences in max workload (P<0.001) and ejection fraction (P=0.013).