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June 7, 2026Schizophrenia Bulletin OpenOpen Access

Development of Physical Activity from Childhood to Adolescence in Offspring at Familial High Risk of Schizophrenia or Bipolar Disorder and Population-Based Controls - the Danish High Risk and Resilience Study

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Authors

ASAnne SøndergaardSRSinnika Birkehøj RohdMSMarta Schiavon

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Overview

Randomized trial examines physical activity outcomes in children at familial high risk for mental disorders, indicating these children are less active than controls.

Key Points

  • The aim is to understand the trajectories of physical activity in children at familial high risk of schizophrenia or bipolar disorder.
  • Longitudinal cohort study involving 367 children at age 11 and 258 at age 15
  • Used accelerometry to measure physical activity levels
  • Analyzed associations with body mass index and motor functioning
  • At age 15, adolescents at familial high risk showed fewer daily steps and less continuous walking than controls (Cohen’s d = 0.38 and 0.43)
  • From ages 11 to 15, step counts declined across groups, with modest increases in moderate-to-high physical activity for high-risk groups but not controls
  • Higher physical activity at age 11 correlated with higher activity at age 15, and increased activity linked to better functioning in adolescents and caregivers.

Cite This Study

Søndergaard et al. (2026) studied this question.

synapsesocial.com/papers/6a250ce97def13d035e1d224https://doi.org/10.1093/schizbullopen/sgag022
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