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October 1, 2018EuroInterventionOpen Access

In the <3% STS score stratum, all-cause mortality or disabling stroke at one year was 1.5% for TAVI vs. 6.5% for SAVR (p=0.04).

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Why the study?

Does TAVI reduce all-cause mortality or disabling stroke compared to SAVR in patients with severe aortic stenosis and STS PROM <3%?

Population

Patients with severe aortic stenosis at intermediate surgical risk based on Heart Team consensus, stratified…

Comparison

Transcatheter aortic valve implantation (TAVI) vs Surgical aortic valve replacement (SAVR)

Design

RCT, randomised to TAVI or SAVR

Follow-up

one year

Authors

PSPatrick W. SerruysRMRodrigo ModoloMRMichael J. Reardon

Discussion

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Overview

May support TAVI in lowest-risk patients; hypothesis-generating SURTAVI subgroup needing dedicated confirmation.

Structured PICO

Does TAVI reduce all-cause mortality or disabling stroke compared to SAVR in patients with severe aortic stenosis and STS PROM <3%?

P
Population
Patients with severe aortic stenosis at intermediate surgical risk based on Heart Team consensus, stratified into STS PROM score categories (<3%, 3 to <5%, and >5%)
I
Intervention
Transcatheter aortic valve implantation (TAVI)
C
Comparator
Surgical aortic valve replacement (SAVR)
O
Outcome
All-cause mortality or disabling stroke at one yearcomposite

In a subgroup analysis of the SURTAVI trial, TAVI was associated with significantly lower rates of all-cause mortality or disabling stroke at one year compared to SAVR in patients with an STS PROM <3%.

Cite This Study

Serruys et al. (2018) studied this question.

synapsesocial.com/papers/6a25998384e798ed748941f9https://doi.org/10.4244/eij-d-18-00460
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