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Investigates HIF-1's role in autophagy to reveal mechanisms in renal fibrosis, implying potential therapeutic targets.
Autophagy has been reported to participate in renal fibrosis, but its role and underlying activation mechanism is unclear. In this study, we report the role of HIF-1 in autophagy activation in models of renal fibrosis and further investigate the underlying mechanism.
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Liu et al. (2024) studied this question.
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