Green α,β-C(sp 3 )–H Difunctionalization of Saturated Cyclic Amines and Ethers through FeCl 3 -Catalyzed Dehydrogenative 4 + 2 Cycloaddition under Air

Key Points

• This research evaluates a simple method for the green difunctionalization of cyclic amines and ethers using iron chloride as a catalyst.
• Utilized FeCl3 as a catalyst for dehydrogenative cycloaddition
• Targeted saturated cyclic amines and ethers
• Assessed yields and functional group compatibility
• Achieved acceptable yields with good functional group compatibility
• Established operational simplicity in the protocol
• Demonstrated effective difunctionalization under air conditions