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The aim is to describe clinicopathological features and treatment outcomes of PMBCL at Siriraj Hospital.

June 8, 2026Open Access

Clinicopathological Features of Primary Mediastinal Large B-cell Lymphoma: A 5-Year Retrospective Study

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The aim is to describe clinicopathological features and treatment outcomes of PMBCL at Siriraj Hospital.
Retrospective study including all diagnosed PMBCL cases from 2020 to 2024.
Data on clinical, pathological, treatment, and survival outcomes retrieved from medical records.
Survival rates estimated using the Kaplan–Meier method.
PMBCL represented 50% of mediastinal lymphoma cases, with a median age of 29 years.
Two-year overall survival rate was 80.1%, and progression-free survival rate was 66.8%.
Common presentations included cough (79.4%), dyspnea (74.3%), and significant elevated LDH in 91.4% of cases.

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Retrospective study describes clinicopathological features and outcomes of PMBCL in a Thai cohort, suggesting importance of accurate diagnostics.

Muang-iam et al. (2026) studied this question.

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Retrospective study describes clinicopathological features and outcomes of PMBCL in a Thai cohort, suggesting importance of accurate diagnostics.