Answers are grounded in this paper and cite their sources.
Evolution in the test tube: With the help of the error-prone polymerase chain reaction as a method for random mutagenesis, an efficient gene-expression system, and a screening test for the rapid identification of enantioselective catalysts, it is possible to increase sequentially the ee value of an unselective lipase-catalyzed ester hydrolysis (see picture on the right).
No takes yet. Share an insight, caveat, or question.
Reetz et al. (1997) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: