Key points are not available for this paper at this time.
Evolution in the test tube: With the help of the error-prone polymerase chain reaction as a method for random mutagenesis, an efficient gene-expression system, and a screening test for the rapid identification of enantioselective catalysts, it is possible to increase sequentially the ee value of an unselective lipase-catalyzed ester hydrolysis (see picture on the right).
Reetz et al. (Tue,) studied this question.