What question did this study set out to answer?

This research aims to assess the prognostic value of preoperative NLR and SII for postoperative pneumonia and pulmonary complications following thoracic surgery.

June 9, 2026Frontiers in MedicineOpen Access

Preoperative neutrophil-to-lymphocyte ratio and systemic immune-inflammation index as prognostic biomarkers for postoperative pneumonia and pulmonary complications after thoracic surgery: a systematic review and meta-analysis

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Authors

XYXinrui YinAerospace Center Hospital DSDu SKing University

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Implication

Systematic review evaluates preoperative biomarkers for pneumonia risk in adults undergoing thoracic surgery, suggesting potential prognostic utility.

Key Points

This research aims to assess the prognostic value of preoperative NLR and SII for postoperative pneumonia and pulmonary complications following thoracic surgery.
Conducted a systematic search of multiple databases until April 2026.
Included observational studies on NLR and SII associations with pulmonary outcomes after lung resection or esophagectomy.
Used random-effects models for analysis and GRADE for evidence certainty evaluation.
Included eight cohort studies with 3,936 patients.
Higher preoperative NLR was associated with approximately twofold increased odds of pneumonia per unit increment and fourfold increase above specific thresholds.
Higher SII indicated over double the odds above specific cut-offs, but confidence intervals reflected low evidence certainty due to limited studies.

Cite This Study

Yin et al. (2026) studied this question.

synapsesocial.com/papers/6a27accaa963992e1626752e https://doi.org/10.3389/fmed.2026.1867440

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Implication

Systematic review evaluates preoperative biomarkers for pneumonia risk in adults undergoing thoracic surgery, suggesting potential prognostic utility.

Preoperative neutrophil-to-lymphocyte ratio and systemic immune-inflammation index as prognostic biomarkers for postoperative pneumonia and pulmonary complications after thoracic surgery: a systematic review and meta-analysis

Discussion

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Implication

Key Points

Cite This Study

Preoperative neutrophil-to-lymphocyte ratio and systemic immune-inflammation index as prognostic biomarkers for postoperative pneumonia and pulmonary complications after thoracic surgery: a systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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