Case report reveals increased flap failure risk in patient with Factor V Leiden deficiency, suggesting need for enhanced guidance.
We report a 63-year-old female with Factor V Leiden deficiency who underwent a left delayed DIEP flap reconstruction with contralateral symmetrising breast reduction following mastectomy. Hypercoagulable disorders are theorised to increase flap failure risk. Current evidence and operative guidance are limited. A focused review of the literature is provided.
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Quinn et al. (2026) studied this question.
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