High-density and resolution epicardial mapping provides novel insights into the pathophysiology and electrical phenomena underlying atrial fibrillation.
How does high-density and resolution epicardial mapping (HDREM) contribute to novel insights into the pathophysiology underlying atrial fibrillation?
High-density and resolution epicardial mapping provides critical insights into the complex electrical substrates and mechanisms underlying atrial fibrillation, which may guide more effective substrate-based treatments.
In this review, we evaluate how high-density and resolution epicardial mapping (HDREM) contributed to novel insights into the pathophysiology underlying atrial fibrillation (AF). The limited efficacy of pulmonary vein isolation for more persistent types of AF emphasizes the need for a more substrate-based treatment approach. However, mechanisms underlying mechanisms and substrates of AF are still incompletely understood and require detailed investigation. Electrical phenomena including signal fractionation, cycle length variability, focal waves, rotational activity, conduction velocity, -block, -anisotropy and endo- epicardial asynchrony during the different clinical stages of AF are discussed.
Boer et al. (Mon,) conducted a review in Atrial fibrillation. High-density and resolution epicardial mapping (HDREM) was evaluated. High-density and resolution epicardial mapping provides novel insights into the pathophysiology and electrical phenomena underlying atrial fibrillation.
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