The resorcinol–octadecanal cyclotetramer 1 forms an ion channel in planar lipid bilayers. A stable conductance level is observed with well-defined transitions between open and closed states. The channel discriminates K+ from Na+ ions as well as cations from anions (for example, K+ from Cl−), as indicated by permeability ratios of 3 and 20, respectively. Rb+ ions block the K+ ion current.
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Tanaka et al. (1995) studied this question.
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