Surgical Management of Omphalocele–Exstrophy–Imperforate Anus–Spinal Defect (OEIS) Complex: A Case Report

The OEIS complex—comprising omphalocele, cloacal exstrophy, imperforate anus, and spinal defects—remains among the most uncommon and severe neonatal malformations, and its reconstruction demands carefully sequenced operations. We describe a male neonate managed through a two-stage strategy. On the second day of life, omphalocele repair, adhesiolysis, terminal ileostomy, and cecal resection were undertaken, while bladder closure was intentionally postponed. At eight months, hemibladder approximation and abdominal wall reconstruction followed. Eleven-month follow-up showed stable clinical status, functioning ileostomy, and resolving right-sided hydronephrosis. This case supports staged reconstruction as a feasible pathway in this rare entity.