Systematic review and meta-analysis shows AVAPS reduces intubation rates in acute hypercapnic respiratory failure, suggesting potential preference for selected patients.
> 0.63). In adults with acute HRF, AVAPS lowers intubation rates compared with BiPAP, without clear short-term survival benefit. Physiological outcomes and LOS appear equivalent. AVAPS may be preferred for selected patients, though larger, high-quality RCTs are needed to confirm the mortality effects.
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Gregory et al. (2026) studied this question.
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