An unusual case of Salmonella breast abscess in a non-lactating female

Salmonella typhi is primarily associated with enteric fever; localized extraintestinal infections are uncommon. Breast abscess due to Salmonella typhi in non-lactating women is extremely rare. A 27-year-old non-lactating woman presented with fever and a painful swelling in the right breast. Ultrasonography revealed a well-defined hypoechoic collection suggestive of an abscess. Surgical drainage was performed, and microbiological analysis of pus demonstrated gram-negative bacilli. Culture yielded non-lactose fermenting colonies, which were identified as Salmonella typhi using standard biochemical tests and serotyping. The isolate was susceptible to most antibiotics but resistant to fluoroquinolones. This case highlights an unusual presentation of Salmonella typhi infection. It emphasizes the need for microbiological evaluation in atypical breast abscesses to ensure accurate diagnosis and appropriate antimicrobial therapy.