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June 10, 2026International Journal of Molecular SciencesOpen Access

TRPM7 in Peripheral and Central Immune Cells: Emerging Roles in Neuroinflammation and Neurological Disease

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Authors

KBKyra S. BrewerZXZhi-Gang Xiong冷冷田东

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Overview

This review summarizes TRPM7's involvement in neuroinflammation and immune cell function in neurological diseases.

Key Points

  • The aim is to explore TRPM7's roles in immune cell regulation and neuroinflammation processes.
  • Review of recent literature on TRPM7 functions in various immune cell types.
  • Analysis of TRPM7 impacts on innate and adaptive immune responses.
  • Discussion of the implications for neuroinflammatory and neurodegenerative conditions.
  • TRPM7 is crucial for immune cell development and activation, influencing inflammatory responses.
  • Emerging evidence highlights TRPM7's role in neuroinflammatory diseases through its activity in immune cells.
  • Understanding TRPM7 functions may lead to new therapeutic strategies for neurological disorders.

Cite This Study

Brewer et al. (2026) studied this question.

synapsesocial.com/papers/6a28ff6a6f82f25be989c591https://doi.org/10.3390/ijms27125157
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