Perception and Uptake of Tetanus Toxoid Vaccination Among Female Undergraduates in Lagos State University

Tetanus is a life-threatening disease caused by toxins produced by Clostridium tetani, with a global maternal and neonatal mortality burden of approximately 309,000 deaths and a case fatality rate of 35%. Women of reproductive age are particularly vulnerable, and the World Health Organization recommends a full course of tetanus toxoid (TT) immunisation to provide long-term protection. TT vaccination stimulates protective immunity lasting 10 to 30 years, while incomplete vaccination leaves individuals susceptible to infection, including from tetanus-prone wounds sustained during injuries or specific activities such as military training. Despite its proven efficacy, financial constraints in many regions necessitate donor support to achieve optimal immunisation coverage. Ensuring complete TT vaccination for women of reproductive age is essential for preventing maternal and neonatal tetanus and reducing overall morbidity and mortality. Understanding the knowledge and perception of TT vaccination among target populations, such as female undergraduates, is critical for designing effective public health interventions and promoting adherence to vaccination schedules