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This study aims to estimate the cross-section and yield for producing 177Lu using 176Yb as a target by simulating a cyclotron-based approach.

Optical and Back-Shifted Fermi Gas Models in Estimation of Cross-Section and Yield Amounts of 176Yb(d,p/x) Nuclear Reactions

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Randomized trial estimates cross-section and yield amounts in 176Yb(d,p/x) reactions, suggesting implications for radio-immunotherapy.

This study aims to estimate the cross-section and yield for producing 177Lu using 176Yb as a target by simulating a cyclotron-based approach.
Simulated a cyclotron in Karaj, Iran, with a maximum deuteron energy of 14 MeV using SRIM and TALYS software.
Calculated cross-sections and production yields of the reaction Yb(d,p)Yb*Lu at varying deuteron energies.
Applied optical model parameters and back-shifted Fermi gas model to estimate energy level densities for the compound nucleus Yb.
Maximum cross-section for the (d,p) reaction was 125 mb at 10.5 MeV, and for (d,x) reaction, it was 121 mb at 9.5 MeV.
Production yields were estimated at 118 MBq/A.h at 10.5 MeV and 315 MBq/A.h at 14 MeV, leading to 318 MBq/A for 1h of irradiation.
Identified that the BSFGM may not accurately predict branching ratios for isotopes due to model limitations.

Abdollah Khorshidi (2026) studied this question.

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