Evaluation of the mechanical properties of strontium-releasing scaffolds for bone repair in biomechanical fractures: comparative analysis

Bone repair and regeneration have been greatly improved through the development of strontium-releasing scaffolds. This review considers the diverse mechanical properties of strontium-releasing scaffolds from various engineering perspectives, including the design and production of strontium-releasing structures, as well as how strontium can affect the biological properties of these scaffolds. Previous research has demonstrated that strontium positively impacts bone metabolism, and has also shown that strontium release will have a significant impact on the mechanical performance of strontium-releasing scaffolds. Using a combination of both in vitro and in vivo studies, we discuss the ways in which strontium released from scaffolds will also improve the mechanical properties and bioactivity of scaffolds. In particular, we focus on the importance of achieving an optimal combination of mechanical strength and the bioactive properties of strontium-releasing scaffolds to promote effective bone regeneration. In addition, we discuss some of the current barriers to developing clinical applications of strontium-releasing scaffolds and suggest future research efforts to further develop the potential clinical uses of strontium-releasing scaffolds. Strontium releasing scaffolds have the potential to be an important tool in orthopedic and dental tissue engineering.