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June 10, 2026Ibnosina Journal of Medicine and Biomedical SciencesOpen Access

Prediction of In-Hospital Mortality in Patients with NSTEMI Using Systemic Immune-Inflammation Index and Systemic Inflammatory Response Index: A Retrospective Prognostic Study

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Authors

BKBurak KafalıSESerkan Emre EroğluMİMehmet Muzaffer İslam

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Overview

Retrospective study compares SII and SIRI for predicting in-hospital mortality in NSTEMI, suggesting potential biomarkers.

Key Points

  • This study aims to compare the effectiveness of SII and SIRI in predicting in-hospital mortality for NSTEMI patients.
  • Utilized a retrospective observational study design involving 157 NSTEMI patients.
  • Calculated SII and SIRI using hematological parameters from blood samples at emergency department admission.
  • Performed statistical tests and multivariable logistic regression analysis to identify predictors.
  • In-hospital mortality occurred in 15 patients (9.6%) with significantly higher SII (p = 0.002) and SIRI (p < 0.001).
  • ROC analysis showed AUC of 0.748 for SII and 0.804 for SIRI, indicating better prognosis assessment with SIRI.
  • Only SII was independently associated with in-hospital mortality (OR: 1.001; 95% CI: 1.000–1.002; p = 0.041).

Cite This Study

Kafalı et al. (2026) studied this question.

synapsesocial.com/papers/6a28fff36f82f25be989cb39https://doi.org/10.1055/s-0046-1824345
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