Key result
Open adrenalectomy for borderline oncocytic adrenal adenoma yields no recurrence at 18 months.
Why the study?
Adrenal oncocytic neoplasms are rare non-functioning adrenal tumors that present a difficult preoperative diagnosis.
Case Report (n=1)
No
Adrenal oncocytic neoplasms should be considered in the differential diagnosis of large adrenal incidentalomas, and complete resection is essential for accurate diagnosis and risk stratification.
Supports considering AONs in large non-functioning adrenal masses; single case leaves open malignant risk stratification.
Adrenal oncocytic neoplasms (AONs) are rare non-functioning adrenal tumors with difficult preoperative diagnosis. We report a 40-year-old man with an 11 cm adrenal mass, negative hormonal workup, and imaging findings. The patient underwent open adrenalectomy. Histopathology showed oncocytic adenoma with borderline/uncertain malignant potential per Lin–Weiss–Bisceglia criteria (size >10 cm, necrosis). Postoperative course was uneventful, with no recurrence at 18 months. AONs should be considered in large adrenal incidentalomas; complete resection is essential for diagnosis, risk stratification, and follow-up.
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Kamoun et al. (2026) conducted a case report in Oncocytic Adrenal Adenoma (n=1). Open adrenalectomy was evaluated on Recurrence. Open adrenalectomy for an 11 cm oncocytic adrenal adenoma with borderline malignant potential resulted in an uneventful postoperative course with no recurrence at 18 months.
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