Key result
Open nephrectomy and adrenalectomy for a 93-mm mass reveals a rare nonfunctioning borderline malignant adrenal oncocytoma.
Why the study?
Adrenal oncocytomas are rare, nonfunctioning tumors whose nonspecific imaging often impedes preoperative diagnosis.
Case Report (n=1)
This case highlights the incidental discovery of a rare, large nonfunctioning adrenal oncocytoma with borderline malignant potential during cardiac evaluation, successfully treated with surgical resection.
Documents rare borderline-malignant adrenal oncocytoma found on cardiac evaluation; leaves open reliable preoperative differentiation strategies.
Introduction Adrenal oncocytomas are rare, nonfunctioning tumors composed of eosinophilic oncocytic cells whose nonspecific imaging often impedes preoperative diagnosis. We report a case of a large nonfunctioning adrenal oncocytoma with borderline malignant potential, incidentally discovered during cardiac symptom evaluation. Case Presentation A 77‐year‐old man with an incidentally discovered retroperitoneal tumor was referred to Urology for further evaluation. Contrast‐enhanced CT revealed a 93‐mm lobulated mass with heterogeneous enhancement abutting the left kidney's upper pole. Given the tumor's size, open left nephrectomy and adrenalectomy were performed. Gross and histopathology revealed a yellowish, solid adrenal tumor composed predominantly of oncocytic cells with no invasion of the kidney. Immunohistochemistry revealed a low Ki‐67 index (approximately 2%). The tumor was classified as having borderline malignant potential (Lin–Weiss–Bisceglia criteria). Conclusion We present a rare case of nonfunctioning adrenal oncocytoma with borderline malignant potential. Long‐term follow‐up is recommended due to the uncertain malignant potential.
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Yamakawa et al. (2026) conducted a case report in Adrenal oncocytoma (n=1). Open left nephrectomy and adrenalectomy was evaluated on Histopathological diagnosis and tumor classification. Open left nephrectomy and adrenalectomy of a 93-mm retroperitoneal mass revealed a rare nonfunctioning adrenal oncocytoma with borderline malignant potential.
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