Assesses nasal function improvement in hereditary hemorrhagic telangiectasia patients, suggesting a promising intervention.
BACKGROUND: Epistaxis related to hereditary hemorrhagic telangiectasia (HHT) can be life-threatening and decreases quality of life (QoL). Current medical and surgical options are limited, particularly in the advanced stages of the disease. METHODS: We assess the feasibility and outcome of HHT-related epistaxis management by resurfacing the nasal cavity with an endoscopically placed free flap. The Epistaxis Severity Score (ESS) was compared to the preoperative score at one-year post-surgery. RESULTS: The nasal cavity was successfully resurfaced with a radial forearm free flap. The ESS decreased from 8.9 to 3.5 one-year postoperatively. CONCLUSION: Resurfacing endoscopic free flap (REFF) is a safe and effective procedure for the management of HHT-related epistaxis refractory to other treatment options. Nasal function is maintained, with a significant long-term decrease in epistaxis.
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Haugen et al. (2026) studied this question.
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