What does this research mean for the field?

Structured exercise interventions, specifically resistance and aerobic training, consistently improve muscle performance and functional outcomes in patients on long-term glucocorticoid therapy, offering a promising adjuvant strategy to mitigate treatment-induced adverse effects. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To assess the interplay between glucocorticoid therapy and physical exercise, providing clinical recommendations for this specific population.

June 10, 2026Sports MedicineOpen Access

Physical Exercise as an Adjuvant to Glucocorticoid Therapy: Clinical Recommendations and Evidence Review

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Authors

PEPaula Etayo-UrtasunNavarrabiomed MAMikel L. Sáez de AsteasuUniversidad Publica de Navarra MIMikel IzquierdoUniversidad Publica de Navarra

Discussion

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Overview

Narrative review evaluates exercise impact on glucocorticoid treatment, suggesting tailored recommendations for patients.

Key Points

To assess the interplay between glucocorticoid therapy and physical exercise, providing clinical recommendations for this specific population.
Conducted a narrative and systematic review of 19 studies on exercise interventions in glucocorticoid-treated patients.
Included trials focused on populations with rheumatoid arthritis and systemic lupus erythematosus, totaling n=663, predominantly women.
Evaluated methodological quality using the Risk of Bias 2 tool.
Exercise interventions notably improved muscle performance and functional outcomes in glucocorticoid-treated patients.
Evidence for improvements in bone, cardiometabolic, cognitive, and mental health outcomes was limited or inconsistent.
Resistance training and aerobic exercise were highlighted as crucial elements for optimal exercise prescription.

Cite This Study

Etayo-Urtasun et al. (2026) studied this question.

synapsesocial.com/papers/6a2901536f82f25be989da1e https://doi.org/10.1007/s40279-026-02469-6

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June 10, 2026Sports MedicineOpen Access

Physical Exercise as an Adjuvant to Glucocorticoid Therapy: Clinical Recommendations and Evidence Review

View Full Paper

Ask AI

Bookmark

Authors

PEPaula Etayo-UrtasunNavarrabiomed MAMikel L. Sáez de AsteasuUniversidad Publica de Navarra MIMikel IzquierdoUniversidad Publica de Navarra

Discussion

Member takes

Overview

Narrative review evaluates exercise impact on glucocorticoid treatment, suggesting tailored recommendations for patients.

Key Points

To assess the interplay between glucocorticoid therapy and physical exercise, providing clinical recommendations for this specific population.
Conducted a narrative and systematic review of 19 studies on exercise interventions in glucocorticoid-treated patients.
Included trials focused on populations with rheumatoid arthritis and systemic lupus erythematosus, totaling n=663, predominantly women.
Evaluated methodological quality using the Risk of Bias 2 tool.
Exercise interventions notably improved muscle performance and functional outcomes in glucocorticoid-treated patients.
Evidence for improvements in bone, cardiometabolic, cognitive, and mental health outcomes was limited or inconsistent.
Resistance training and aerobic exercise were highlighted as crucial elements for optimal exercise prescription.

Cite This Study

Etayo-Urtasun et al. (2026) studied this question.

synapsesocial.com/papers/6a2901536f82f25be989da1e https://doi.org/10.1007/s40279-026-02469-6

Also Consider

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