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June 10, 2026Scientific ReportsOpen Access

Clinicopathological characteristics and follow-up outcomes of patients with oral potentially malignant disorders: A 7-year observational cohort study

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Authors

SASahel AzadSTSajad TorkiAMAzra Mohiti

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Overview

Observational cohort study evaluates clinical and histopathological characteristics of OPMDs, suggesting need for early diagnosis and follow-up.

Key Points

  • This study evaluates the characteristics and clinical outcomes of patients diagnosed with oral potentially malignant disorders (OPMDs).
  • Combined retrospective and prospective cohort study design
  • Inclusion of 50 patients with OPMDs referred between 2019 and 2025
  • Data collected through clinician checklists and clinical examinations.
  • 86% of patients showed lichenoid mucositis upon histopathological examination
  • 57% of leukoplakia patients exhibited dysplastic changes
  • 80% of patients had persistent lesion morphology at follow-up.

Cite This Study

Azad et al. (2026) studied this question.

synapsesocial.com/papers/6a2901536f82f25be989da44https://doi.org/10.1038/s41598-026-56478-6
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinicopathological Characteristics of Oral Malignant Lesions and Oral Potentially Malignant Disorders: A Retrospective Hospital‐Based Case Series2026
  2. 2Knowledge About the Importance of Early Diagnosis and Treatment of Oral Potentially Malignant Disorders Among the South Indian Population: An Institutional Retrospective Study2024 · 3 citations
  3. 3Long‐Term Care of OLP Patients: A Retrospective Study From a Single Hospital Outpatient Clinic2026
  4. 4Clinical practice of early screening and risk-stratified management for oral potentially malignant disorders2025
  5. 5Pattern of Progression of Oral Potentially Malignant Disorders From Real-World Data: A 24-Year Study.2026