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October 9, 2025Frontiers in OncologyOpen Access

Clinical practice of early screening and risk-stratified management for oral potentially malignant disorders

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Authors

BGBeibei GeXZXinqiang ZhuMMMeimei Ma

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Overview

Evaluation of risk stratification and multidisciplinary team management improves early diagnosis in patients with oral potentially malignant disorders.

Key Points

  • High-risk patients had a malignant transformation rate of 12.5%, significantly higher than lower-risk groups, indicating effective risk identification.
  • Utilizing a modified scoring system for risk stratification, the MDT model achieved a 91.4% cancer-free survival rate in high-risk OPMD patients.
  • Analysis showed severe epithelial dysplasia, tongue ventral lesions, and betel quid history as independent factors for increased malignant risk.
  • Implementing a structured screening pathway optimizes intervention timing and enhances patient follow-up compliance to 83.3%.

Cite This Study

Ge et al. (2025) studied this question.

synapsesocial.com/papers/68e79cf2ed88661f66c2e0e3https://doi.org/10.3389/fonc.2025.1697676
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