Shows effectiveness of dual-action mitochondrial therapy in rheumatoid arthritis, suggesting improved cellular health.
Dual Renewal Strategy for Rheumatoid Arthritis Inspired by Chinese philosophy, this cover illustrates a dual-action mitochondrial renewal therapy (DAMRT) for rheumatoid arthritis. Like a lotus leaf, a folate-modified macrophage membrane precisely encapsulates healthy mitochondria and AUTAC4. This biomimetic system targets inflamed joints, delivering fresh mitochondria while degrading dysfunctional ones to effectively restore cellular metabolic homeostasis. More details can be found in the Research Article by Ke Xu, Yan Hu, Long Bai, Jiacan Su, and co-workers (DOI: 10.1002/adma.202514070).
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Wang et al. (2026) studied this question.
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