Choroidal Changes After Intravitreal Aflibercept, Faricimab, Brolucizumab, and High Dose Aflibercept in Treatment-Naïve Neovascular AMD

Sam Razavi; Matteo Menna; Serena Fragiotta; Sarah Van Herreweghe; A. Lazzerini; Marco Battist; Federico Beretta; Riccardo Sacconi; Giuseppe Querques

doi:10.1016/j.xops.2026.101275

June 1, 2026Ophthalmology ScienceOpen Access

Choroidal Changes After Intravitreal Aflibercept, Faricimab, Brolucizumab, and High Dose Aflibercept in Treatment-Naïve Neovascular AMD

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Key Points

The aim is to compare structural changes in the choroid after different anti-VEGF treatments in patients with neovascular AMD.
Compared choroidal structural changes after a loading phase of various anti-VEGF agents.
Participants were treatment-naïve individuals diagnosed with neovascular AMD.
Differences in choroidal changes were observed among the various anti-VEGF agents used.
Specific metrics such as thickness and structural integrity were assessed after treatment administration.

Implication

Compares choroidal changes after different anti-VEGF treatments in treatment-naïve neovascular AMD, suggesting varied impacts.

Abstract

Purpose:To compare choroidal structural changes after a loading phase of different anti-vascular endothelial growth factor (VEGF) agents in treatment-naïve neovascular age-related macular degeneration (nAMD).

Discussion

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Cite This Study

Razavi et al. (2026) studied this question.

synapsesocial.com/papers/6a2901886f82f25be989dd2d https://doi.org/10.1016/j.xops.2026.101275

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Choroidal Changes After Intravitreal Aflibercept, Faricimab, Brolucizumab, and High Dose Aflibercept in Treatment-Naïve Neovascular AMD

Key Points

Implication

Abstract

Discussion

Cite This Study

Choroidal Changes After Intravitreal Aflibercept, Faricimab, Brolucizumab, and High Dose Aflibercept in Treatment-Naïve Neovascular AMD

Key Points

Implication

Abstract

Discussion

Cite This Study

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