June 10, 2026European Heart Journal
Acute neurogenic pulmonary oedema following generalized tonic clonic seizure. A case report and a review of the literature
Key result
Generalized tonic-clonic seizures are linked to rare but serious acute neurogenic pulmonary edema.
- n=1
Why the study?
Acute neurogenic pulmonary oedema following a generalized tonic clonic seizure is rare with unknown pathophysiology, but represents a serious complication linked to high mortality and sudden death.
Design
Case report and review of the literature
Authors
Discussion
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Implication
Clinicians should consider neurogenic pulmonary oedema in postictal respiratory failure; this case extends sparse reports but leaves open incidence and prevention data.
Key Points
- To present a case of acute neurogenic pulmonary oedema occurring after a generalized tonic clonic seizure and review its implications.
- Case presentation detailing acute neurogenic pulmonary oedema after seizure
- Literature review on the condition and associated mortality
- Discussion on pathophysiology and treatment importance
- Acute neurogenic pulmonary oedema is a rare but serious complication of seizures, with high associated mortality rates in older individuals.
- Evidence of pulmonary oedema found in recent cases of young epileptics who died suddenly highlights the severe implications of this condition.
Study Design
Type
Case Report (n=1)
Structured PICO
P
Population
A single case report of acute neurogenic pulmonary oedema following a generalized tonic clonic seizure.
Highlights the importance of recognizing acute neurogenic pulmonary oedema as a potentially fatal complication of generalized tonic clonic seizures.
Limitations
- The exact pathophysiology is unknown.
Cite This Study
Fredberg et al. (1988) conducted a case report in Acute neurogenic pulmonary oedema following generalized tonic clonic seizure (n=1). Generalized tonic clonic seizure was evaluated on Acute neurogenic pulmonary oedema. Acute neurogenic pulmonary oedema is presented as a rare but serious complication following a generalized tonic clonic seizure, with an unknown exact pathophysiology.