Key result
A 31-year-old man developed recurrent acute neurogenic pulmonary edema after generalized tonic-clonic seizures, which rapidly resolved within 24 hours with intubation and lung protective ventilation.
Case Report (n=1)
This case highlights that acute neurogenic pulmonary edema can occur recurrently following generalized tonic-clonic seizures and can be managed successfully with supportive care including lung protective ventilation.
Answers are grounded in this paper and cite their sources.
May support lung-protective ventilation for recurrent post-seizure neurogenic edema; hypothesis-generating case report requiring prospective validation.
Acute pulmonary edema following significant injury to the central nervous system is known as neurogenic pulmonary edema (NPE). Commonly seen after significant neurological trauma, NPE has also been described after seizure. While many pathogenic theories have been proposed, the exact mechanism remains unclear. We present a 31-year-old man who developed recurrent acute NPE on two consecutive admissions after experiencing witnessed generalized tonic-clonic (GTC) seizures. Chest radiographs obtained after seizure during both admissions showed bilateral infiltrates which rapidly resolved within 24 hours. He required intubation on each occasion, was placed on lung protective ventilation, and was successfully extubated within 72 hours. There was no identified source of infection, and no cardiac pathology was thought to be contributory.
No takes yet. Share an insight, caveat, or question.
Sacher et al. (2018) conducted a case report in Recurrent acute neurogenic pulmonary edema (n=1). Generalized tonic-clonic seizures was evaluated. A 31-year-old man developed recurrent acute neurogenic pulmonary edema after generalized tonic-clonic seizures, which rapidly resolved within 24 hours with intubation and lung protective ventilation.
Synapse has enriched 10 related papers. Consider them for comparative context: