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The aim is to synthesize data on SARS-CoV-2 seroprevalence to understand infection levels and at-risk populations.

June 23, 2021PLoS ONEOpen Access

Global seroprevalence of SARS-CoV-2 antibodies: A systematic review and meta-analysis

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The aim is to synthesize data on SARS-CoV-2 seroprevalence to understand infection levels and at-risk populations.
Conducted a systematic review and meta-analysis from January to December 2020.
Identified and corrected seroprevalence estimates using Bayesian measurement error models.
Performed meta-analysis and meta-regression to discern demographic prevalence variations.
Identified 968 studies, encompassing 9.3 million participants across 74 countries.
Observed median seroprevalence of 4.5% globally, with significant variation among populations.
Found racial minorities showed higher seroprevalence compared to Caucasians (RR up to 5.47).

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Systematic review estimates SARS-CoV-2 antibody prevalence globally, indicating vulnerable demographics and urgent public health needs.

Bobrovitz et al. (2021) studied this question.

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