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October 1, 2007The Journal of ImmunologyOpen Access

Role of CXCR5 and CCR7 in Follicular Th Cell Positioning and Appearance of a Programmed Cell Death Gene-1High Germinal Center-Associated Subpopulation

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NHNicole M. HaynesPeter MacCallum Cancer CentreCAChristopher D.C. AllenMedical University of South CarolinaRLRobin LesleySeattle Pacific University

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Haynes et al. (2007) studied this question.

synapsesocial.com/papers/6a29ffe35db02c10df7848eahttps://doi.org/10.4049/jimmunol.179.8.5099
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help2005 · 303 citations
  2. 2CXCR5-Dependent Seeding of Follicular Niches by B and Th Cells Augments Antiviral B Cell Responses2005 · 75 citations
  3. 3Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells2005 · 588 citations
  4. 4Subspecialization of Cxcr5+ T Cells2001 · 635 citations
  5. 5Unique gene expression program of human germinal center T helper cells2004 · 256 citations