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June 11, 2026Frontiers in PharmacologyOpen Access

Galactagogue activity of shalukam (Nelumbium speciosum Willd rhizome) compared to domperidone in Wistar albino rats

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Authors

AKAathira S. KumarAmrita Vishwa VidyapeethamKVK. S. VimalaAmrita Vishwa VidyapeethamSPS. PriyaAmrita Vishwa Vidyapeetham

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Implication

Randomized trial compares galactagogue effects on lactation in female Wistar rats, indicating potential benefits of shalukam.

Key Points

  • The study aims to evaluate the galactagogue effects of shalukam compared to domperidone on lactation in Wistar albino rats.
  • Twenty-four female Wistar albino rats divided into four groups, each receiving different treatments.
  • Trial drug groups received shalukam chūrṇa at single and double doses; a standard group received domperidone.
  • Milk yield measured by pre- and post-suckling weight changes after a controlled suckling period.
  • Double-dose shalukam group showed better galactagogue activity than domperidone, with increased serum prolactin and cortisol levels.
  • Single-dose shalukam group also outperformed the domperidone group in milk yield after 10 days.
  • Findings indicate shalukam possesses significant galactagogue potential in lactation enhancement.

Cite This Study

Kumar et al. (2026) studied this question.

synapsesocial.com/papers/6a2a4fa380c8f91e7f39c7d1https://doi.org/10.3389/fphar.2026.1810350
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