What question did this study set out to answer?

This study aims to identify prognostic factors and develop a nomogram for predicting overall survival in patients with stage II-IV epithelial ovarian cancer using SEER data.

June 11, 2026Scientific ReportsOpen Access

Constructing a prognostic survival model for patients with stage II-IV epithelial ovarian cancer: a study based on the SEER database and external validation in China

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This study aims to identify prognostic factors and develop a nomogram for predicting overall survival in patients with stage II-IV epithelial ovarian cancer using SEER data.
Data from the SEER database was used, focusing on patients diagnosed between 2004 and 2020.
Cohorts were randomly divided into training, tuning, and internal validation groups in a 7:2:1 ratio.
Cox regression analyses identified independent prognostic factors, and a nomogram was validated using an external cohort from Chengde Medical University.
The developed nomogram demonstrated a C-index of 0.700 during external validation.
Significant survival differences were observed across risk groups using Kaplan-Meier curves.
Calibration curves and AUC values exceeded 0.7, indicating effective prediction of 1-, 3-, and 5-year survival rates.

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Implication

Randomized trial develops a prognostic model for survival prediction in patients with stage II-IV epithelial ovarian cancer, highlighting its clinical utility.

Cite This Study

Ying et al. (2026) studied this question.

synapsesocial.com/papers/6a2a4fa380c8f91e7f39c7eb https://doi.org/10.1038/s41598-026-56780-3

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Implication

Randomized trial develops a prognostic model for survival prediction in patients with stage II-IV epithelial ovarian cancer, highlighting its clinical utility.

Constructing a prognostic survival model for patients with stage II-IV epithelial ovarian cancer: a study based on the SEER database and external validation in China

Key Points

Discussion

Implication

Cite This Study

Constructing a prognostic survival model for patients with stage II-IV epithelial ovarian cancer: a study based on the SEER database and external validation in China

Key Points

Discussion

Implication

Cite This Study

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