What question did this study set out to answer?

This study aims to describe treatment patterns and survival outcomes for patients with stage III resectable melanoma treated with adjuvant therapies in France.

June 11, 2026Dermatology and TherapyOpen Access

Epidemiology and Treatment Patterns of Stage III Resectable Melanoma Treated with Adjuvant Therapy: A Real-World Study Using the SNDS Database in France

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This study aims to describe treatment patterns and survival outcomes for patients with stage III resectable melanoma treated with adjuvant therapies in France.
Retrospective cohort study using data from the French national health data system (SNDS).
Identified patients initiating adjuvant nivolumab, pembrolizumab, or dabrafenib-trametinib between January 2019 and December 2021.
Outcomes assessed included recurrence-free survival and overall survival using Kaplan-Meier estimator.
2612 patients initiated adjuvant therapy: 1483 (56.8%) received NIVO, 635 (24.3%) had PEM, and 494 (18.9%) had DT.
At 36 months, RFS was 50.7% (NIVO), 52.7% (PEM), and 48.3% (DT); OS was 81.8% (NIVO), 82.3% (PEM), and 74.4% (DT).
Immunotherapy constituted 75% of therapies at recurrence for patients treated with NIVO/PEM and 55% for those with DT.

Authors

SMS. MonestierAssistance Publique Hôpitaux de Marseille SBS. BranchouxBristol-Myers Squibb (France)LCLouis ChillottiGeosciences Consultants

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Implication

Retrospective cohort study analyzes treatment patterns and survival outcomes in French patients with stage III melanoma, suggesting optimization need.

Cite This Study

Monestier et al. (2026) studied this question.

synapsesocial.com/papers/6a2a503380c8f91e7f39cc7b https://doi.org/10.1007/s13555-026-01813-y

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Implication

Retrospective cohort study analyzes treatment patterns and survival outcomes in French patients with stage III melanoma, suggesting optimization need.

Epidemiology and Treatment Patterns of Stage III Resectable Melanoma Treated with Adjuvant Therapy: A Real-World Study Using the SNDS Database in France

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Discussion

Implication

Cite This Study

Epidemiology and Treatment Patterns of Stage III Resectable Melanoma Treated with Adjuvant Therapy: A Real-World Study Using the SNDS Database in France

Key Points

Discussion

Implication

Cite This Study

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