What question did this study set out to answer?

This research aims to explore the relationship between hypertrophic cardiomyopathy and atypical atrial flutter.

June 11, 2026Heart Rhythm O20 citationsOpen Access

Complex Atrial Substrate in Hypertrophic Cardiomyopathy Presenting as Right Pulmonary Vein–Related Atypical Atrial Flutter

TVThai Duy VoCho Ray Hospital TCTing‐Yuan ChangNational Yang Ming Chiao Tung University WYW C YuNational Yang Ming Chiao Tung University

Key Result

Hypertrophic cardiomyopathy involves diffuse atrial remodeling and fibrosis that predispose patients to uncommon right inferior pulmonary vein-related atypical atrial flutter.

Key Points

This research aims to explore the relationship between hypertrophic cardiomyopathy and atypical atrial flutter.
Identified patients with hypertrophic cardiomyopathy presenting atrial flutter
Examined the structure of atrial substrates
Analyzed the association with right inferior pulmonary vein reentry
Atypical atrial flutter was observed in patients with significant atrial fibrosis
Right pulmonary vein reentry was a noted mechanism of atrial flutter
Slow conduction in remodeled atrial tissue significantly contributed to arrhythmia incidence

Structured PICO

Population

Patients with hypertrophic cardiomyopathy (HCM) presenting with atypical atrial flutter (AFL) related to right inferior pulmonary vein (RIPV) reentry

Highlights the uncommon presentation of right inferior pulmonary vein-related atypical atrial flutter arising from complex atrial substrate in patients with hypertrophic cardiomyopathy.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Hypertrophic cardiomyopathy (HCM) involves diffuse remodeling of both the ventricles and atria, with atrial fibrosis and slow conduction predisposing to atrial tachyarrhythmias. Atypical atrial flutter (AFL), particularly related to right inferior pulmonary vein (RIPV) reentry, is uncommon.

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