Screening for Major Depression in Post-Myocardial Infarction Patients: Operating Characteristics of the Beck Depression Inventory-II
Key result
The Beck-Depression Inventory-II effectively screened for major depression in post-MI patients, with an optimal cutoff of ≥16 yielding 88.2% sensitivity, 92.1% specificity, and an AUC of 0.96.
Why the study?
Does the Beck Depression Inventory-II (BDI-II) accurately screen for major depressive disorder in post-myocardial infarction patients?
Population
131 post-myocardial infarction patients admitted to an urban academic medical center, assessed within 72…
Comparison
Beck Depression Inventory-II and its cognitive… vs Semi-structured interview for depression
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Supports BDI-II screening in acute post-MI patients; leaves open prospective validation before routine adoption.
Study Design
Type
Cross-Sectional (n=131)
Multicenter
No
Structured PICO
Does the Beck Depression Inventory-II (BDI-II) accurately screen for major depressive disorder in post-myocardial infarction patients?
P
Population
131 post-myocardial infarction patients admitted to an urban academic medical center who completed depression screening within 72 hours of symptom onset.
E
Exposure
Beck Depression Inventory-II (BDI-II) and its cognitive subscale (BDI-II-cog)
C
Comparator
Semi-structured interview for depression (reference standard for MDD diagnosis)
O
Outcome
Diagnostic operating characteristics (sensitivity, specificity, positive and negative predictive values, overall correct classification, likelihood ratios, and AUC) for major depressive disorder
Main Result
Effect estimate: AUC 0.96
The BDI-II and its cognitive subscale are highly sensitive and specific tools for screening major depressive disorder in patients immediately following a myocardial infarction.
Cite This Study
Huffman et al. (2010) conducted a cross-sectional in Major depression in post-myocardial infarction patients (n=131). Beck-Depression Inventory-II (BDI-II) vs. Semi-structured interview for depression was evaluated on Major depression (MDD) diagnosis (AUC 0.96). The Beck-Depression Inventory-II effectively screened for major depression in post-MI patients, with an optimal cutoff of ≥16 yielding 88.2% sensitivity, 92.1% specificity, and an AUC of 0.96.