Light-Driven Iron-Mediated Thiotrifluoromethylation of Alkenes Using CF ₃ CO ₂ H

June 9, 2026Organic LettersOpen Access

View Full Paper

Ask AI

Bookmark

Share

Key Points

This research investigates a method for thiotrifluoromethylation of alkenes using iron salts under light irradiation.
Used iron(III) salts in a three-component reaction under purple-light irradiation to produce trifluoropropyl sulfides.
Employed aryl benzenesulfonothioates as arylthio donors for the reaction.
Evaluated product scope and functional group tolerance.
Successfully generated diverse aryl 3,3,3-trifluoropropyl sulfides with broad functional group tolerance.
Demonstrated the feasibility of late-stage modifications of complex molecules with these products.
Provided a scalable synthetic route to fluorinated sulfur-containing compounds.

Explores thiotrifluoromethylation of alkenes using iron salts, highlighting new fluorinated compounds.

No abstract yet. The journal hasn't published one we can show.

No takes yet. Share an insight, caveat, or question.

Zhou et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark

Share