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June 11, 2026Headache and Pain ResearchOpen Access

Comments on “Brain Glymphatic and Lymphatic Systems in Migraine: Mechanistic Insights and Neuromodulation Perspectives with an Emphasis on Ultrasound-Based Approaches”

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Comments on the impact of the glymphatic and lymphatic systems on migraine, highlighting ultrasound approaches.

This commentary aims to explore the relationship between glymphatic and lymphatic systems in migraine and the potential for ultrasound-based neuromodulation.
Review of literature regarding glymphatic and lymphatic systems in relation to migraine.
Discussion of ultrasound-based neuromodulation techniques.
Increased understanding of mechanisms involved in migraine related to cerebrospinal fluid dynamics.
Potential for ultrasound to enhance treatments targeting the glymphatic and lymphatic systems.

Soo-Jin Cho (2026) studied this question.

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