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This review examines the link between gut microbiota composition and ADHD, focusing on diversity and microbial alterations.

June 11, 2026MicroorganismsOpen Access

Gut Microbiota Composition and Diversity in Attention-Deficit/Hyperactivity Disorder: A Systematic Review

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Systematic review investigates gut microbiota changes in ADHD, suggesting implications for treatment strategies.

This review examines the link between gut microbiota composition and ADHD, focusing on diversity and microbial alterations.
Systematic search of PubMed, Scopus, and Web of Science following PRISMA guidelines.
Inclusion of 23 studies published between 2015 and 2025 that analyze gut microbiota in ADHD.
Assessment of microbial diversity using alpha and beta-diversity metrics.
Most studies showed no significant differences in alpha-diversity between ADHD and control groups.
Beta-diversity indicated significant differences in microbial composition between ADHD and control groups.
ADHD was associated with decreased Alistipes and butyrate-producing bacteria, and increased Roseburia and Agathobacter.

Rodrigues et al. (2026) studied this question.

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