Key result
High-risk PE in ICU patients is linked to ~9-fold higher hospital mortality versus non-high-risk cases.
Why the study?
The study was conducted to describe the short-term and long-term mortality of pulmonary embolism patients admitted to the ICU.
Does high-risk status increase hospital and 1-year mortality in adult patients admitted to the ICU with pulmonary embolism?
Cohort (n=10,210)
Yes
Does high-risk status increase hospital and 1-year mortality in adult patients admitted to the ICU with pulmonary embolism?
Absolute Event Rate: 25.4% vs 2.8%
High-risk pulmonary embolism patients admitted to the ICU have significantly higher hospital and 1-year mortality compared to non-high-risk patients, highlighting the need for careful management in this population.
High-risk PE status flags ICU patients for intensified monitoring; this observational link leaves open whether targeted therapies alter outcomes.
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Mandigers et al. (2026) conducted a cohort in Pulmonary embolism (n=10,210). High-risk pulmonary embolism vs. Non-high-risk pulmonary embolism was evaluated on Hospital mortality. High-risk pulmonary embolism in ICU patients was associated with higher hospital mortality compared to non-high-risk pulmonary embolism (25.4% vs 2.8%).
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