What question did this study set out to answer?

The study aims to identify biopsychosocial factors that predict higher mental well-being trajectories following adverse childhood experiences (ACEs).

June 11, 2026Psychological MedicineOpen Access

Strengths-based resilience: the biopsychosocial factors that differentiate 12-year mental well-being trajectories following adverse childhood experiences

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Randomized trial identifies factors enhancing well-being trajectories in individuals with and without ACEs, suggesting intervention targets.

The study aims to identify biopsychosocial factors that predict higher mental well-being trajectories following adverse childhood experiences (ACEs).
Sample of 889 individuals analyzed using logistic regression models to differentiate well-being trajectories.
Factors assessed included childhood adversity characteristics, demographic factors, health and lifestyle, and psychological functioning.
The analysis compared non-ACE and ACE samples to identify predictors of resilience and risk trajectories.
Higher education and better physical health predict higher well-being across both samples.
In the ACE sample, modifiable factors like parenting style, relationship status, and conscientiousness further differentiate resilience.
Non-ACE sample revealed polygenic well-being scores and family history of mental illness as additional predictors.

Connon et al. (2026) studied this question.

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Randomized trial identifies factors enhancing well-being trajectories in individuals with and without ACEs, suggesting intervention targets.