Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 11, 2026Veterinary ResearchOpen Access

Variation of rabbit serum IgA in relation to RHDV vaccination and infection: implications for serological diagnosis and epidemiological investigations

View Full Paper
Ask AI
Bookmark
Share

Authors

LCLorenzo CapucciVGVittoria Di GiovanniMSMichele Schiavitto

Discussion

Loading...

Member takes

Overview

Randomized trial examines serum IgA response to RHDV vaccination and infection, indicating implications for diagnosis and epidemiology.

Key Points

  • This research investigates the IgA response in rabbits following RHDV vaccination and natural infection to improve serological diagnosis.
  • Two independent vaccination experiments were conducted with rabbits to measure serum IgA levels.
  • Sampling of nine multivaccinated does took place over 3 months on a farm where an RHDV outbreak occurred.
  • A parallel survey examined IgA levels in 61 young rabbits in separate sheds on the farm.
  • Serum IgA was present in trace amounts in about half of vaccinated rabbits, increasing significantly only after live RHDV challenge.
  • Constant medium-to-high IgA levels were observed in only three older multivaccinated does, coinciding with the outbreak.
  • A high percentage of IgA-positive rabbits was identified in one specific shed.

Cite This Study

Capucci et al. (2026) studied this question.

synapsesocial.com/papers/6a2a50e080c8f91e7f39d50fhttps://doi.org/10.1186/s13567-026-01774-2
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Serological Survey for RHD Antibodies in Rabbits from Two Types of Rabbit Breeding Farms2016 · 9 citations
  2. 2Field evaluation of YURVAC® RHD vaccine-induced humoral immunity in intensive meat rabbit farms2026
  3. 3IDENTIFICATION AND CHARACTERIZATION OF THE CURRENTLY CIRCULATING RABBIT HEMORRHAGIC DISEASE VIRUS ISOLATES2024
  4. 4Vaccination Against Rabbit Hemorrhagic Disease Virus 2 Using a Baculovirus Recombinant Vaccine Provides Durable Immunity in Rabbits2024
  5. 5Antibody response of endangered riparian brush rabbits to vaccination against rabbit hemorrhagic disease virus 22024 · 1 citations