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In vitro assessment characterizes optical quality and vision range of a new intraocular lens, indicating its effectiveness for small pupils.
PURPOSE: To perform a comprehensive in vitro optical assessment of the RayOne Galaxy intraocular lens (IOL) (Rayner Intraocular Lenses, Ltd) to characterize its optical quality and functional visual range. METHODS: Three samples of the +20.00 diopters (D) RayOne Galaxy IOL were assessed using the OptiSpheric IOL PRO2 (Trioptics GmbH) bench. All measurements used polychromatic light and a model cornea inducing +0.27 µm of spherical aberration. Modulation transfer function (MTF), through-focus MTF (TF-MTF), area under the MTF (MTFa), and simulated visual acuity (SimVA) were evaluated across pupil diameters of 2 to 4.5 mm. Photic phenomena susceptibility was also assessed via point spread function (PSF) imaging. RESULTS: The Galaxy demonstrated robust optical quality and an extended functional vision for small pupils (2 to 3 mm). At these apertures, the SimVA remained ≤0.2 logarithm of the minimum angle of resolution (logMAR) across a wide defocus range (+1.00 to -3.00 D). The Galaxy showed a distinct higher plateau in the 0.00 to -2.00 D defocus range on the TF-MTF curve for small pupils. PSF analysis also demonstrated a compact central peak and minimal halo rings. However, a significant decline in objective metrics, including SimVA, was observed with increasing defocus for pupils >3.5 mm. CONCLUSIONS: The Galaxy demonstrated an extended range of vision with good optical quality and a low degree of positive dysphotopsia, particularly at small pupil sizes. Optical performance at intermediate and near distances tends to decline notably as pupil diameter increases.
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Kim et al. (2026) studied this question.
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