What question did this study set out to answer?

To evaluate the efficacy and safety of automated insulin delivery systems compared to conventional insulin strategies in adults with type 2 diabetes.

June 11, 2026Systematic ReviewsOpen Access

Automated insulin delivery in type 2 diabetes: a meta-analysis of randomized trials protocol

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To evaluate the efficacy and safety of automated insulin delivery systems compared to conventional insulin strategies in adults with type 2 diabetes.
Systematic review of randomized controlled trials evaluating automated insulin delivery in adults with T2DM.
Comprehensive literature search spanning multiple databases including MEDLINE, EMBASE, and Cochrane CENTRAL until November 30, 2025.
Data extraction and risk of bias assessment will be carried out by two independent reviewers using the Cochrane Risk of Bias 2 tool.
Pooled estimates of efficacy and safety will be calculated using random-effects inverse-variance meta-analysis.
The review will assess the magnitude of benefit and safety profile of automated insulin delivery systems in routine practice.
Certainty of evidence will be rated using GRADE.

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Protocol evaluates efficacy and safety of automated insulin delivery in adults with type 2 diabetes, informing clinical practice.

Gordillo-Rosas et al. (2026) studied this question.

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