Epidermal Inclusion Cyst of the Median Raphe of the Penis: A Case Report

Median raphe cysts represent infrequent benign lesions that develop due to abnormalities during embryonic formation of the urethral folds. Epidermal inclusion cysts arising along this anatomical line are particularly rare and can be mistaken for other penile swellings. They often appear as small, firm white or yellow swelling causing discomfort or tenderness. It can be congenital or acquired by epithelial cell implantation into the skin. It frequently occurs in young men often appearing in the second to third decade, although they are present from childhood. We describe a case involving a 24 months-old male who presented with a painless cystic lesion along the median raphe of the penis since birth. The swelling was managed by complete surgical removal, and histological evaluation confirmed the diagnosis of an epidermal inclusion cyst. Recognition of this condition is important to ensure correct diagnosis and appropriate treatment.