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Case report demonstrates anaphylactic shock after rocuronium use in a 42-year-old man, highlighting the need for prompt management.
Perioperative anaphylactic shock is a rare but potentially fatal complication of general anesthesia. Neuromuscular blocking agents, particularly rocuronium, are among the most frequently implicated pharmacological agents. We report the case of a 42-year-old man with no known allergic history who developed severe anaphylactic shock a few minutes after anesthetic induction for surgical fixation of an intra-articular elbow fracture. The diagnosis was confirmed by a significant elevation of plasma tryptase levels and later by specialized allergy testing. The clinical course was favorable following intensive management, including oxygen therapy with 100% FiO₂, intravenous epinephrine, and advanced resuscitative measures. This case highlights the importance of early recognition, aggressive management, and systematic allergological investigation to prevent re-exposure.
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N.ElHanafiSebti et al. (2026) studied this question.
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