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June 12, 2026The Journal of Infection in Developing CountriesOpen Access

Correlation of hs-CRP and T lymphocyte subsets with severity and prognosis in elderly pulmonary infection

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Authors

YCYuehua ChenBGI Group (China)ZLZ LiuHuzhou Central HospitalYCYuehua ChenBGI Group (China)

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Implication

Randomized trial investigates disease severity and treatment outcomes in elderly pulmonary infection, suggesting hs-CRP monitoring aids prognosis.

Key Points

  • The study aims to evaluate the relationship between hs-CRP levels, T lymphocyte subsets, and disease severity in elderly patients with pulmonary infections.
  • Included 85 elderly patients with respiratory infections and 79 healthy controls.
  • Measured hs-CRP and T lymphocyte subsets, analyzing correlations with disease severity and clinical pulmonary infection score (CPIS).
  • Compared pre- and post-treatment levels of hs-CRP and T lymphocyte subsets based on treatment response.
  • Patients with pulmonary infection had significantly lower CD4+ counts and CD4+/CD8+ ratios than controls (p < 0.05).
  • Severe cases exhibited higher hs-CRP and lower CD4+ levels compared to non-severe cases (p < 0.05).
  • ROC analysis indicated an hs-CRP cutoff difference of 5.31 had 86.67% sensitivity for treatment outcomes.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba1438101cf8926f00c46https://doi.org/10.3855/jidc.22001
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